<i><b>Arabidopsis thaliana</b></i> <b>Fibrillin 3a binds saturated fatty acids of chloroplast membranes</b>.

ABSTRACT: Fibrillins (FBNs) are conserved plastid lipid-associated proteins involved in lipid storage, stress adaptation and plastid ultrastructure. While several Arabidopsis thaliana FBNs have been functionally characterized, the biochemical properties of the thylakoid-associated FBN3a remain poorly understood. AlphaFold modeling revealed that AtFBN3a adopts an eight-stranded β-barrel fold typical of the lipocalin family, with high-confidence predictions for the core β-strands and conservation of the structurally conserved region 1 (SCR1) motif that stabilizes the barrel and defines the ligand-binding cavity. This structural topology is also shared with AlphaFold models of the other members of the family in A. thaliana. Consistent with the lipocalin-like structural and s

SUBMITTER: Herrera-Tequia A 

PROVIDER: S-EPMC12674411 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature