Autoimmune diseases as pre-existing conditions and sequelae of post COVID-19 condition in a Massachusetts community based observational study of COVID-19 patients.

ABSTRACT: Between 10%-26% of COVID patients develop Post COVID condition (PCC). The complex interaction between autoimmunity and SARS-CoV-2 is emerging as an important challenge and an opportunity to improve diagnosis and treatment of immune mediated chronic illnesses. In a retrospective cohort study using electronic health records from a Massachusetts group medical practice, we identified 38,327 patients with a COVID-19 diagnosis and 1,143 with a PCC diagnosis from 1/1/2020 to 6/25/2023. We investigated the hypotheses that auto-immune diseases-1) increase risk of developing PCC; 2) were more likely to develop after COVID-19; and 3) medical utilization would be higher in patients with a PCC diagnosis. We compared COVID-19 patients with and without a PCC diagnosis. We evaluated demographics, PCC symp

SUBMITTER: Sama SR 

PROVIDER: S-EPMC12674521 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature