Genetic characterization of equine arteritis virus associated with outbreaks in the UK, 2019.

ABSTRACT: Equine arteritis virus (EAV) is the causative agent of equine viral arteritis, a notifiable respiratory and reproductive disease of equids that causes significant losses to the equine industry. This study presents a comprehensive analysis of two EAV outbreaks in the UK in 2019, combining virus isolation, sequencing and phylogenetic analysis to provide a holistic understanding of EAV dynamics in these outbreaks. Genetic characterization revealed that all outbreak strains were similar to viruses detected in the UK and Europe from 2004 to 2011, belonging to phylogroup D and clustering in two groups as expected based on epidemiological profiling. Bayesian phylogenetic analysis indicated the direction of transmission. The 2019 EAV strains showed maximum variability in glycoprotein (GP) 3, follo

SUBMITTER: Bhat S 

PROVIDER: S-EPMC12674535 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature