Factors influencing drug-susceptible tuberculosis treatment outcomes in Romania and Ukraine.

ABSTRACT:

Background

Tuberculosis (TB) remains one of the most globally impactful infectious diseases, with a recorded mortality of 1.6 million in 2022. In Romania and Ukraine, two high burden countries in the context of the WHO European region, treatment is geared towards cure; however, this path is paved with significant challenges, from morbidity to loss to follow-up.

Methods

A retrospective study was performed for drug-susceptible TB patients hospitalised in three TB expertise centres in Romania and Ukraine using routinely collected data. Univariable and multivariable logistic regression analyses were used to assess predictors of three treatment outcomes: unfavourable outcomes, loss to follow-up, and death.

Results

A total of 838 patients diagnosed with drug-susceptible TB

SUBMITTER: Margineanu I 

PROVIDER: S-EPMC12674542 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature