Development and Application of Automated Vocal Fold Tracking Software in a Rat Surgical Model.

ABSTRACT:

Objective

The rat is a widely used model for studying vocal fold (VF) function after recurrent laryngeal nerve injury, but common techniques for evaluating rat VF motion remain subjective and imprecise. To address this, we developed a software package, called RatVocalTracker1.0 (RVT1.0), to quantify VF motion and tested it on rats with iatrogenic unilateral vocal fold paralysis (VFP).

Methods

A deep neural network was trained to identify the positions of the VFs and arytenoid cartilages (ACs) in transoral laryngoscope videos of the rat glottis. Software was developed to estimate glottic midline, VF displacement, VF velocity, and AC angle. The software was applied to laryngoscope videos of adult rats before and after right recurrent and superior laryngeal nerve transection (N

SUBMITTER: Pennington-FitzGerald W 

PROVIDER: S-EPMC12674628 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature