Discovery of Bioactive Properties in the Seagrass <i>Ruppia maritima</i> Extract: A Triplatform Assessment of Antioxidant, Antidiabetic, Antibacterial, Cytotoxic, and Analgesic Activities.

ABSTRACT: Ruppia maritima, a seagrass, was investigated for its potential antioxidant, antidiabetic, antibacterial, cytotoxic, and analgesic activities. The acetone extract of its leaves (AERM) was studied using in vitro, in vivo, and in silico methods. To determine its secondary metabolites, the total phenolic and flavonoid content was measured. Antioxidant capacity was evaluated using DPPH and ABTS radical scavenging assays, while antidiabetic potential was assessed through the alpha-amylase inhibition assay. The disc diffusion method was used to examine antibacterial effects, and cytotoxicity was determined using both the brine shrimp lethality assay and the MTT assay on HeLa cells. Analgesic activity was tested via the acetic acid-induced writhing test and formalin-induced paw licking tes

SUBMITTER: Payel IN 

PROVIDER: S-EPMC12674862 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature