An anti-inflammatory reliever algorithm approach to asthma management in adults: an open-label, single-arm trial.

ABSTRACT:

Background

The stepwise approach to asthma management is a key feature of guidelines, yet knowledge of its implementation in clinical practice is limited. Our objective was to evaluate the implementation of an anti-inflammatory reliever (AIR) stepwise algorithm.

Methods

Between December 2020 and July 2022, we conducted a 52-week, open-label, single-arm trial of 100 adults aged 18-75 with asthma, with 25 patients each on Global Initiative for Asthma 2018 treatment steps 1, 2, 3 and 4 at baseline. Patients were assigned to an AIR algorithm, with budesonide-formoterol 200/6 μg, one actuation as-needed (Step 1), one actuation twice-daily plus as-needed (Step 2), or two actuations twice-daily plus one as-needed (Step 3), depending on baseline treatment. Treatment steps were adjus

SUBMITTER: Bruce P 

PROVIDER: S-EPMC12675026 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature