Serum metabolites with diagnostic potential in prostate cancer and the inhibitory effects of alpha-Tocomonoenol on prostate cancer cells.

ABSTRACT:

Introduction

Prostate cancer is the most common malignant disease of the male urinary system, seriously endangering men's health. Currently, early detection of prostate cancer mainly relies on prostate-specific antigen (PSA) screening; however, PSA is characterized by high sensitivity but low specificity. Patients with PSA levels in the gray zone (4-10ng/ml) are at risk of excessive medical interventions, highlighting the great significance of exploring new diagnostic indicators for prostate cancer.

Methods

A total of 60 subjects were enrolled in this study, including 30 prostate cancer patients and 30 benign prostatic hyperplasia patients. Non-targeted metabolomics analysis was performed on the subjects, and the profiling results were statistically analyzed. A diagnostic mo

SUBMITTER: Shen Y 

PROVIDER: S-EPMC12675167 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature