Feasibility of Therapist-Driven MR-Guided Adaptive Radiotherapy for Oligometastatic Disease: Geometric Accuracy and Dosimetric Impact.

ABSTRACT:

Introduction

MRI-guided adaptive radiation therapy (ART) is the resource-intensive process of daily treatment plan modification. This study aims to demonstrate the feasibility of radiation therapist (RT)-led MRI-guided ART for oligometastatic disease (OMD) by comparing geometric accuracy and dosimetric differences between RT and radiation oncologist (RO) re-contouring.

Methods

Five RTs and five ROs retrospectively re-contoured gross target volumes (GTVs) and organs-at-risk (OARs) for eight OMD cases. RT and RO contours were compared against consensus RO Simultaneous Truth and Performance Level Estimation (RO-STAPLE) contours using the Dice similarity coefficient (DICE), mean distance to agreement (MDA), planning target volume (PTV) D95 and OAR D0.5cc using the Wilcoxon signe

SUBMITTER: Moreira A 

PROVIDER: S-EPMC12675315 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature