Topology-driven energy transfer networks for upconversion stimulated emission depletion microscopy.

ABSTRACT: Lanthanide-doped upconversion nanoparticles enable upconversion stimulated emission depletion microscopy with high photostability and low-intensity near-infrared continuous-wave lasers. Controlling energy transfer dynamics in these nanoparticles is crucial for super-resolution microscopy with minimal laser intensities and high photon budgets. However, traditional methods neglect the spatial distribution of lanthanide ions and its effect on energy transfer dynamics. Here, we introduce topology-driven energy transfer networks in lanthanide-doped upconversion nanoparticles for upconversion stimulated emission depletion microscopy with reduced laser intensities, maintaining a high photon budget. Spatial separation of Yb³⁺ sensitizers and Tm³⁺ emitters in 50-nm core-shell

SUBMITTER: Gu W 

PROVIDER: S-EPMC12675517 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature