Radiation-induced maculopathy and fluocinolone acetonide implant.

ABSTRACT:

Purpose

This study evaluates the effectiveness of fluocinolone acetonide (FAc) implants in managing radiation maculopathy, a complication of ocular irradiation. The primary outcomes were the change in best-corrected visual acuity (BCVA) and central foveal thickness (CFT), and the impact on therapeutic burden and intraocular pressure (IOP).

Methods

This was a retrospective, multicenter, observational study conducted across three French oncology-ophthalmology reference centers. Twelve eyes of twelve patients with radiation maculopathy following ocular irradiation for uveal melanoma were included. All patients received at least one injection of the FAc implant between February 2021 and July 2023. Data on tumor characteristics, lens status, BCVA, CFT, IOP, and SD-OCT findings we

SUBMITTER: Fricker J 

PROVIDER: S-EPMC12675579 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature