Infective endocarditis and relationship with diabetes mellitus - Patient characteristics, microbial etiology and mortality.

ABSTRACT:

Purpose

Infective endocarditis (IE) has been associated with severe outcomes when complicated by diabetes mellitus (DM). We aimed to report characteristics, microbial etiology, and mortality for patients with IE stratified by DM from a nationwide cohort.

Methods

We used Danish registries, and patients with first-time IE (2010-2020) were stratified by DM. We computed inverse Kaplan-Meier estimates for one-year mortality from admission. We computed multivariable adjusted Cox regression for the adjusted one-year mortality from admission and discharge.

Results

We identified 6,211 patients with first-time IE; 1,503 (24.2%) with DM (26.1% Type 1 DM, 68.1% male, median age 72.7 years); 4,708 (75.8%) did not have DM (67.0% male, median age 72.4 years). Patients with IE and DM

SUBMITTER: Jensen AD 

PROVIDER: S-EPMC12675667 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature