Corneal stability comparison between prophylactic cross-linking with laser refractive surgery technique versus laser refractive surgery technique alone for myopia: a meta-analysis.

ABSTRACT:

Purpose

To summarize whether corneal cross-linking (CXL) with laser refractive surgery improves corneal stability more than laser surgery alone for myopia.

Methods

Five electronic databases were systematically searched from inception to Aug, 2023. Studies comparing the effects of prophylactic corneal CXL with laser refractive surgery technique versus laser refractive surgery technique alone in myopic eyes were included. The included articles regarding prophylactic CXL combination with laser refractive surgery technique, riboflavin was all delivered into the stroma with similar accelerated protocols (irradiance of 30mW/cm² for 60-90 seconds). Primary outcome measures included post-operative changes of keratometry, refraction, corneal thickness, endothelial cell den

SUBMITTER: Yang SA 

PROVIDER: S-EPMC12675695 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature