Clinical scoring system to differentiate melioidosis from other documented causes of community-acquired bacterial pneumonia: a retrospective cohort study.

ABSTRACT:

Background

Melioidosis, caused by Burkholderia pseudomallei, is an underdiagnosed cause of community-acquired pneumonia (CAP) in India. Due to overlapping features with other bacterial pneumonias and limited access to culture facilities, early diagnosis and treatment remain challenging. This study aimed to develop a clinical scoring system to distinguish melioidosis from other bacterial causes of CAP in an endemic setting.

Methods

We conducted a retrospective cohort study of 337 patients with radiologically confirmed blood or respiratory culture-positive CAP cases at a tertiary care hospital in South India from 2017 to 2023. This included 55 melioidosis cases and 282 controls with other documented bacterial etiologies. Demographic, clinical, laboratory, and radiological vari

SUBMITTER: Gupta N 

PROVIDER: S-EPMC12675767 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature