Gender Differences in Trajectories of Depressive Symptoms Among Talkspace Clients: Naturalistic Observational Study.

ABSTRACT:

Background

Gender minority populations experience an increased risk of depression and report significant barriers to accessing mental health services. While digital mental health (DMH) technologies may address barriers, it remains unclear how gender minority clients engage with DMH services and if DMH improves their clinical outcomes.

Objective

This naturalistic study explored gender differences in 15-week clinical outcomes of clients receiving technology-mediated psychotherapy from a large DMH provider.

Methods

This study used observational data of clients who signed up for Talkspace (Talkspace, Inc) between February 2017 and July 2021. The analytic sample included Talkspace clients (N=20,156) with a baseline 8-item Patient Health Questionnaire (PHQ-8) score ≥10. Par

SUBMITTER: Romanelli M 

PROVIDER: S-EPMC12675994 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature