Quality of different brands of clarithromycin tablets marketed in Ethiopia; implications for the future.

ABSTRACT:

Background

There are concerns with the availability of substandard antibiotics across Africa, including Ethiopia, exacerbating high levels of antimicrobial resistance (AMR). There are ongoing initiatives across Africa to reduce their availability to reduce AMR, including Pan-African registration, coordination with Interpol, and increasing surveillance. Consequently, the objective of the study was to evaluate the quality of different brands of clarithromycin tablets currently marketed in Ethiopia as a key antibiotic.

Methods

A total of 120 tablets of 12 different brands of clarithromycin 500 mg tablets were purchased from 12 different community pharmacies. Quality control tests, including visual inspection, thickness, diameter, hardness, friability, weight variation, disinteg

SUBMITTER: Bayu WT 

PROVIDER: S-EPMC12676004 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature