Multiple Chronic Conditions Before Pregnancy and Risk of Adverse Maternal Health Outcomes: Population-Based Cohort Study.

ABSTRACT:

Objective

To assess the risks of perinatal emergency department (ED) use, hospitalisation and severe maternal morbidity or mortality (SMM-M) associated with preconception MCC, according to the number of chronic conditions, complex MCC and co-occurring cardiometabolic conditions.

Design

Population-based cohort study.

Setting

Ontario, Canada.

Population

Females aged 13-54 years, with a recognised pregnancy, 2012-2021.

Methods

Modified Poisson regression was used to generate adjusted relative risks (aRRs) according to the number of chronic conditions, complex MCC (≥ 3 chronic conditions affecting ≥ 3 body systems) and co-occurring cardiometabolic conditions. aRRs were adjusted for age, parity, income quintile, rurality and immigrant/refugee status.

Main

SUBMITTER: Brown HK 

PROVIDER: S-EPMC12676192 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature