Glycaemic Control in Women With Type 1 Diabetes and Preeclampsia Risk: A Nationwide Cohort Study.

ABSTRACT:

Objective

No large-scale studies exist investigating glycaemic control around conception and preeclampsia risk.

Design

Population-based nationwide cohort study using the National Diabetes Register and other health registers.

Setting

Sweden.

Population

Singleton pregnancies between 2003 and 2019 (N = 1 689 301); 4429 with type 1 diabetes (T1DM) and 1 684 872 without.

Methods

The main exposure was having a pre-gestational diagnosis of T1DM (first diagnosis anytime ≤ 91 days after conception and ≥ 1value of glycated haemoglobin (HbA1c) within ±90 days from conception). Peri-conceptional glycaemic control was categorised using the most recent HbA1c measurement (mmol/mol: < 48; 48-61; 62-75; ≥ 76). Unexposed were women without any diabetes diagnosis (≤ 91 day

SUBMITTER: Holowko N 

PROVIDER: S-EPMC12676193 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature