Andrographolide Selectively Inhibits the Growth of LA7 Mammary Adenocarcinoma Cells.

ABSTRACT: Breast cancer (BC) causes significant mortality and morbidity, specifically in women globally. The first line of available therapies are far from satisfactory due to their adverse side effects, drug resistance, and reoccurrence of the cancer. As a result, natural source-based complementary medicines with anticancer activity and lesser side effects are widely investigated. Andrographolide (AGL), an active phytomolecule of Andrographis paniculata, exhibits diverse pharmacological activities against various diseases. The purpose of the study is to investigate the potential anticancer activity of AGL on LA7 cells, an in vitro mammary tumor model system, to understand its interaction with red blood cells (RBC) and effect on their membrane integrity. LA7 is a mammary adenocarcinoma

SUBMITTER: Roy K 

PROVIDER: S-EPMC12676339 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature