Is cognitive reserve associated with cognitive function across stroke severity? A longitudinal study among Chinese stroke patients.

ABSTRACT:

Background

Cognitive decline is common after stroke. This study assessed the longitudinal associations between cognitive reserve and post-stroke cognitive function and tested whether these associations differ across patients' stroke severity.

Methods

A longitudinal survey was conducted among 371 patients with acute ischemic stroke from four stroke centers in China from 2022 to 2023. Eligible patients were recruited at acute stage and followed up at 3 and 6 months after onset. Cognitive reserve was assessed by Cognitive Reserve Index questionnaire within 7 days after stroke onset. Cognitive function was assessed by Montreal Cognitive Assessment, Changsha Version at each time point. Stroke severity was assessed using the National Institutes of Health Stroke Scale at admission.

SUBMITTER: Ou Y 

PROVIDER: S-EPMC12676486 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature