Safety aspects of <i>de novo</i> DCB-only PCI-a practical checklist and a simplified revised dissection classification.

ABSTRACT: There is increasing use of drug-coated balloons (DCBs) in de novo coronary disease, supported by an ever-expanding evidence base. However, DCB-only angioplasty requires a slightly modified lesion preparation strategy to ensure an optimal angioplasty result and minimise the risk of vessel-threatening dissection. In this article, we discuss the importance of optimal lesion preparation and vessel safety based on clinical and angiographic findings, as well as the selection and deployment of appropriate DCB. We outline a new and simplified classification of dissections: those that are safe to leave untreated (type 1) and those that require modification or stenting (type 2). We also present this classification in a simple graphical format. Finally, we provide a checklist for the complete

SUBMITTER: Corballis NH 

PROVIDER: S-EPMC12676487 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature