Individual-specific resting-state networks predict language dominance in drug-resistant epilepsy.

ABSTRACT:

Importance

Identifying language dominance is a crucial step in epilepsy surgery planning. We applied a precision functional brain mapping approach to estimate individual-specific cortical resting-state networks in drug-resistant epilepsy and predict language dominance.

Objective

To determine whether individual-specific cortical network topography can predict task-based language dominance in drug-resistant epilepsy.

Design

Retrospective case-control study conducted between January 2024 and August 2025.

Setting

Multicentre population-based study including healthy participants from the Human Connectome Project, and participants with drug-resistant epilepsy from the National Institutes of Health (NIH) and the University of Iowa.

Participants

Eligible partici

SUBMITTER: Jun Rui ML 

PROVIDER: S-EPMC12676542 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature