Weight gain during tuberculosis treatment increases the risk of post-tuberculosis metabolic syndrome.

ABSTRACT:

Background

Little is known about the relationship between weight gain during treatment and the subsequent risk of cardiovascular and metabolic (cardiometabolic) diseases. We assessed the relationship between changes in body mass index (BMI) during TB treatment with prevalence post-TB metabolic syndrome, a strong predictor of cardiometabolic diseases.

Methods

We enrolled a prospective cohort of individuals successfully treated for TB disease in Tbilisi, Georgia, from 2019 - 2022. Eligible participants were HIV-negative individuals aged ≥16 years with newly diagnosed and laboratory-confirmed pulmonary TB. Our study exposure was the relative change in BMI from treatment initiation to treatment completion, dichotomized using ≥5% relative increase cut-off. Our primary study outco

SUBMITTER: Salindri AD 

PROVIDER: S-EPMC12676555 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature