Epidemiologic and Environmental Investigations of Reported Hantavirus Cases Inform Exposure Risk in California, 1993-2020.

ABSTRACT: From 1993 to 2020, 89 hantavirus cases were reported in California residents. Fifty-six (63%) were male, mean age was 41.5 years old, and 28 (31%) of the cases were fatal. The majority of cases were classified as hantavirus pulmonary syndrome, and infections peaked during summer and spring. A total of 70 environmental investigations were conducted for 77 cases (87%). Visual evidence of rodent activity was detected in 52 (74%) of the investigations, and 36 patients (40%) reported direct contact with rodents or having cleaned rodent-affected areas. In total, 1,353 rodents (73%) captured during the investigations were Peromyscus maniculatus, and 264 (20%) tested positive for Sin Nombre virus (SNV) antibodies. Probable exposure locations were identified for 81 cases (91%), with the majority of

SUBMITTER: Jackson BT 

PROVIDER: S-EPMC12676593 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature