Incidence of frailty-related fracture among Medicaid beneficiaries living with HIV and cancer: A cohort study.

ABSTRACT:

Background

People living with HIV (PLWH) are at increased risk for frailty-related fracture. Limited evidence suggests recent diagnosis of non-AIDS defining cancer (NADC) is a risk factor for fracture among PLWH. We evaluated frailty-related fracture by HIV and cancer status to inform the burden of fracture among PLWH.

Methods

We included 14,554,711 beneficiaries without HIV and 159,188 beneficiaries with HIV who were 30-64 years old enrolled in Medicaid between 2001-2015 in 14 states. HIV, NADC, and fracture diagnoses were identified from inpatient and other non-prescription claims. We calculated age-specific fracture incidence per 100 person-years and 95% confidence intervals for beneficiaries with no NADC or HIV, NADC only, HIV only, or both. We estimated the cumulative i

SUBMITTER: Zhang X 

PROVIDER: S-EPMC12676673 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature