Prognostic implications of quantified coronary atherosclerosis and myocardial perfusion in diabetes.

ABSTRACT:

Background

Coronary artery disease (CAD) is a major contributor to cardiovascular events in individuals with diabetes. Quantification of coronary atherosclerotic burden is now feasible from coronary computed tomography angiography (CTA) whereas positron emission tomography (PET) enables quantitative assessment of myocardial perfusion. We studied the prognostic implications of quantitatively measured coronary plaque burden and myocardial perfusion in diabetic vs. non-diabetic patients with suspected CAD.

Methods

In this observational cohort study, 1311 symptomatic patients with suspected CAD underwent coronary CTA and [¹⁵O]H₂O PET perfusion imaging. Coronary plaque burden was quantified using artificial intelligence-based analysis and reported as percent

SUBMITTER: Maenpaa M 

PROVIDER: S-EPMC12676773 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature