Quantifying the versatility of routinely measured prognostic factors.

ABSTRACT:

Background

Some prognostic factors (PF) are "versatile" insofar as they predict diverse health outcomes (age is an exemplar par excellence). In this study, we sought to quantify the versatility of commonly measured PFs.

Methods

Participants from the UKB (UK biobank) study were followed from enrolment until the date of outcome or censoring. Over 800 incident adverse outcomes were considered, based on a unique 3-digit ICD code (A00, A01, A02, etc.). Twenty-four routine PFs-including renal, liver function and blood count biomarkers-featured in this analysis. Cox regression was used to determine the association between each PF with time to each outcome event. The number of statistically significant associations, direction of the association (positive/negative) and the median log

SUBMITTER: Innes H 

PROVIDER: S-EPMC12676796 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature