Real-World Use of Phentermine and Topiramate for Adolescent Obesity: Retrospective Effectiveness and Safety Analysis.

ABSTRACT: Background: National guidelines support adjunct anti-obesity medications to treat adolescent obesity. The combination of phentermine and topiramate is accessible and efficacious in controlled trials, but very little clinic-based data exist. We sought to describe prescribing characteristics, effectiveness, and safety of phentermine and/or topiramate in a clinical setting. Methods: A retrospective chart review was conducted among patients prescribed phentermine and/or topiramate for obesity in a pediatric obesity management program between 2019 and 2021. Patient and provider characteristics, percent BMI change, vital signs, laboratory tests, and discontinuation data were assessed. Results: Patients (n = 126) with mean age of 15.5 years, 50% Hi

SUBMITTER: Batt CE 

PROVIDER: S-EPMC12677284 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature