TEG ® 6s Heparin Neutralization Cartridge for Hemostatic Assessment of Patients Undergoing Cardiovascular Surgery.

ABSTRACT:

Background

Heparin administration can limit viscoelastic testing. The cartridge-based TEG ® 6s thromboelastography system (Haemonetics Corp., USA) uses heparinase to neutralize heparin effects. This study aimed to validate the TEG 6s global hemostasis-heparin neutralization cartridge, recently cleared by the U.S. Food and Drug Administration, in heparinized patients undergoing cardiovascular surgery with cardiopulmonary bypass or cardiovascular procedures without cardiopulmonary bypass and liver transplantation.

Methods

Adult patients undergoing cardiovascular surgery/invasive cardiac procedures with planned use of unfractionated heparin were included in this multicenter observational study. Blood samples were obtained before heparin administration, after heparin administrat

SUBMITTER: Adelmann D 

PROVIDER: S-EPMC12677338 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature