Evaluation of umbilical cord blood serum eye drops for severe dry eye in two distinct populations-Sjogren's syndrome and mustard gas-induced ocular injury: Protocol for a pilot randomized clinical trial.

ABSTRACT:

Background

Human umbilical cord blood (HUCB) serum eye drops contain growth factors, neurotrophic agents, and antimicrobial compounds that may promote ocular surface healing and regeneration. Sjögren's syndrome is a chronic autoimmune condition characterized by reduced tear production and ocular surface damage, often resulting in severe dry eye symptoms. Mustard gas chemical veterans also suffer from similar debilitating ocular complications due to chronic inflammation and meibomian gland dysfunction. While conventional treatments offer symptomatic relief, they lack essential components of natural tears.

Materials and methods

This pilot randomized controlled trial will evaluate the efficacy of HUCB eye drops in three patient groups: (A) Sjögren's patients treated with HUCB d

SUBMITTER: Daryabari SH 

PROVIDER: S-EPMC12677545 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature