Elevated blood urea nitrogen-to-creatinine ratio predicts short-term mortality in intensive care unit patients with ischemic stroke: Evidence from a multicenter cohort.

ABSTRACT:

Background

The blood urea nitrogen-to-creatinine ratio (BUCR) has emerged as a potential biomarker for predicting the prognosis of Intensive Care Unit (ICU) patients. However, its relationship with short-term mortality in patients with ischemic stroke (IS) remains controversial. This study aimed to investigate the association between BUCR and 28-day in-hospital mortality in ICU IS patients.

Methods

This retrospective cohort study utilized data from the eICU Collaborative Research Database (2014--2015). A total of 2,702 ICU patients with IS were included. The BUCR was calculated on the basis of initial blood urea nitrogen and serum creatinine levels obtained within the first 24 hours of ICU admission. The association between BUCR and 28-day in-hospital mortality was assessed

SUBMITTER: Luwen H 

PROVIDER: S-EPMC12677572 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature