Antenatal wildfire smoke exposure and preterm birth phenotypes: A retrospective cohort study.

ABSTRACT:

Background

Novel evidence suggests an association of wildfire smoke exposure with preterm birth (PTB). However, the mechanism and exposure timing of this association are poorly understood.

Objective

We estimate the association of wildfire smoke on PTB phenotypes (spontaneous PTB [sPTB] and medically indicated PTB [mPTB]) as well as hypertensive disorders of pregnancy (HDP).

Study design

Birth cohort data from singleton livebirths in California from 2007 to 2012 were combined with daily zip code-level estimates of wildfire smoke intensity. Satellite-based estimates of wildfire smoke plume boundaries and high-resolution gridded estimates of surface particulate matter 2.5 (PM_2.5) concentrations were used to calculate smoke exposure from 4 weeks preconception t

SUBMITTER: Waldrop AR 

PROVIDER: S-EPMC12677857 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature