Pressure Support Ventilation in Neurosurgical Patients: Can We Safely Reduce Assistance? Evaluation of Neurosurgical Patients' Ventilation Distribution - The ENVISION Study.

ABSTRACT:

Objectives

To identify the prevalence of over-assistance from mechanical ventilation (MV) and to assess whether reducing MV support could be done safely in neurosurgical ICU patients in terms of risk of under-assistance and brain's oxygenation.

Design

Prospective observation study.

Setting

Neurosurgical trauma ICU, Toronto, ON, Canada.

Patients

Twenty-seven brain-injured patients on MV having indication of a spontaneous breathing trial (SBT).

Interventions

Level of pressure support ventilation (PSV).

Measurements and main results

In neurosurgical patients, regional ventilation distribution using electrical impedance tomography, patient's respiratory drive (airway occlusion at 100 ms [P0.1]), respiratory muscle pressure (Pmus), diaphragm and parast

SUBMITTER: Phoophiboon V 

PROVIDER: S-EPMC12677866 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature