Detection and severity stratification of chronic liver disease using magnetic resonance intravoxel incoherent motion and elastography.

ABSTRACT:

Background

With chronic liver disease (CLD) rising globally, noninvasive methods are needed to stratify early, intermediate, and advanced CLD with and without clinically significant portal hypertension (CSPH).

Purpose

To analyze the combined diagnostic value of intravoxel incoherent motion (IVIM) and liver stiffness (LS) from magnetic resonance elastography (MRE) for CLD stage discrimination vs secondary single-parameter analyses.

Materials and methods

This retrospective cross-sectional study included 185 patients who underwent 3T liver MRI, including MRE and IVIM, between March 2016 and November 2023. Patients with CLD were grouped based on their liver fibrosis degree into early CLD (F0-F1; n = 21), intermediate CLD (F2; n = 19), advanced CLD (F3-F4,

SUBMITTER: Catucci D 

PROVIDER: S-EPMC12677949 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature