Prevalence of Large-for-Gestational Age and Macrosomia Among Livebirths in 23 Low- and Middle-Income Countries Between 2000 and 2021: An Individual Participant Data Analysis.

ABSTRACT:

Objective

To examine the prevalence of large-for-gestational age (LGA) and macrosomia in 23 countries between 2000 and 2021.

Design

Descriptive multi-country secondary data analysis.

Setting

Subnational, population-based cohort studies (k = 45 for LGA, k = 25 for macrosomia) in 23 low- and middle-income countries (LMICs).

Population

Liveborn infants.

Methods

We conducted a secondary analysis of individual-level data from the Vulnerable Newborn Measurement Collaboration, using INTERGROWTH-21st standards to define LGA (> 90th centile for gestational age and sex) and macrosomia (≥ 4000 g, regardless of gestational age). We included LMIC population-based datasets with reliable gestational age and birthweight data, excluding studies with small sample sizes, h

SUBMITTER: Kirakoya-Samadoulougou F 

PROVIDER: S-EPMC12678062 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature