Comparing the clinical efficacy of hemoporfin-mediated photodynamic therapy for port wine stains in children with prior pulsed dye laser treatment history.

ABSTRACT:

Background

Hemoporfin-mediated photodynamic therapy (HMME-PDT) is an effective and safe therapeutic modality for port wine stains (PWS). However, the clinical efficacy is influenced by multiple factors. This study aimed to evaluate the efficacy of HMME-PDT for children with PWS who have a prior history of pulsed dye laser (PDL) treatment.

Methods

Clinical data were collected from children with PWS who received HMME-PDT treatment. The patients were divided into two groups: patients without PDL treatment history as the No PDL group and patients with a history of PDL as the Prior PDL group. The correlations between clinical efficacy and gender, age, lesion location, lesion color, dermoscopic vascular features, and number of treatments were analyzed in children with PWS.

Resu

SUBMITTER: Wang X 

PROVIDER: S-EPMC12678093 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature