Prognostic value of the Geriatric Nutritional Risk Index in sepsis-associated acute kidney injury: a retrospective cohort study.

ABSTRACT:

Background

The Geriatric Nutritional Risk Index (GNRI) is a simple and objective tool for assessing nutritional status. It has shown prognostic value in patients with acute kidney injury (AKI). However, evidence in sepsis-associated AKI (S-AKI) remains limited, especially among patients receiving continuous renal replacement therapy (CRRT).

Methods

This retrospective cohort study included 773 critically ill S-AKI patients who received CRRT, using data from the publicly available Dryad database. Patients were stratified into tertiles based on GNRI values. Cox proportional hazards models were employed to assess the association between GNRI and 28-day and 90-day all-cause mortality, with the lowest tertile serving as the reference group. Kaplan-Meier survival analyses were used

SUBMITTER: Ren G 

PROVIDER: S-EPMC12678099 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature