Relationship of TMAO levels with vascular function in patients with hypertension.

ABSTRACT: Increased trimethylamine-N-oxide (TMAO) level is a known risk factor for hypertension. Hypertension is associated with vascular dysfunction. Recently, it has been shown that endothelial function is impaired in relation to an increase in TMAO level. However, there is no information on the relationship between TMAO levels and vascular function in patients with hypertension. The purpose of this study was to evaluate the independent variables for circulating TMAO levels and to evaluate the relationships of circulating TMAO levels with vascular function assessed by flow-mediated vasodilation (FMD) and nitroglycerine-induced vasodilation (NID) in patients with hypertension. This study was a cross-sectional study. A total of 333 subjects with hypertension were enrolled in this study. Log TMAO lev

SUBMITTER: Yamaji T 

PROVIDER: S-EPMC12678174 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature