Profiling endothelial function, oxidative stress and inflammatory biomarkers in individuals with various cardiovascular risk factors: the African-PREDICT study.

ABSTRACT: Cardiovascular risk factors are known to contribute to cardiovascular disease (CVD) development by inducing endothelial activation, increasing oxidative stress and pro-inflammation. The early interaction between these pathways and individual cardiovascular (CV) risk factors is poorly understood. We profiled a range of circulating endothelial function, oxidative stress and inflammatory biomarkers and explored their associations with individual CV risk factors in young (20-30 years, n = 1196) adults without self-reported chronic conditions or medication use. Participants were stratified into CV risk factor groups based on blood pressure, anthropometrical measurements, biochemical analyses and questionnaire data. We identified several differences in biomarker levels between control (without a

SUBMITTER: Jacobs A 

PROVIDER: S-EPMC12678181 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature