Integrative metabolomic and transcriptomic analyses reveal flavonoid biosynthesis pathway in Eupatorium lindleyanum.

ABSTRACT: Eupatorium lindleyanum, a medicinal plant from the Asteraceae family, is renowned for its diverse bioactive compounds, particularly flavonoids, which contribute to its various pharmacological activities. However, the biosynthetic pathway and regulatory mechanisms underlying flavonoid production in Eupatorium lindleyanum remain largely unexplored. In this study, an integrated metabolomic and transcriptomic approach was employed to investigate flavonoid biosynthesis in Eupatorium lindleyanum. Samples from four different tissues (roots, stems, leaves, and flowers) were analysed to identify variations in differentially expressed genes (DEGs) and differentially accumulated metabolites (DAMs). A total of 330 differentially accumulated flavonoid metabolites (DFMs) and 53,610 DEGs were identified.

SUBMITTER: Wang Y 

PROVIDER: S-EPMC12678412 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature