Whole-genome characterization of Newcastle disease virus isolates of sub-genotype VII.1.1 from chickens in Ethiopia.

ABSTRACT: Newcastle disease (ND) is a serious poultry disease in Ethiopia. F gene sequences have shown that the velogenic Newcastle disease virus (NDV) sub-genotype VII.1.1 is prevalent in Ethiopia and other East African countries. However, the F gene sequence alone is not enough to fully understand the pathogenicity, antigenicity, and epidemiological characteristics of NDVs. Whole-genome characterizations of currently circulating virus strains are needed to understand the molecular basis of the pathogenicity and antigenicity differences between vaccine and field strains. In this study, we obtained the complete genome sequences of seven NDV sub-genotype VII.1.1 isolated from chicken farms in Ethiopia and compared them with closely related NDVs and vaccine strains. Whole-genome sequencing revealed th

SUBMITTER: Mihiretu BD 

PROVIDER: S-EPMC12678514 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature