Functional Neurological Disorder Following COVID-19: Results From a Large International Electronic Health Record Database.

ABSTRACT:

Background

Following COVID-19, an increased risk of neurological and psychiatric sequelae has been reported. Viral illnesses commonly trigger functional neurological disorder (FND). However, mechanisms beyond immediate biological effects may contribute to FND after COVID-19. While FND cases have been observed after COVID-19, the overall risk and contributing factors remain unclear. In this retrospective cohort study, we compared the rates of FND post-COVID-19 to other respiratory tract infections (RTIs), assessed the influence of disease severity, and the characteristics of newly diagnosed patients.

Methods

We used TriNetX, a global electronic health record network. In total, 2,740,094 COVID-19 cases and 1846 post-COVID-19 FND cases were analysed. We compared FND incidence b

SUBMITTER: Berlot R 

PROVIDER: S-EPMC12678839 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature