Increasing trend in fusidic acid resistance among MRSA isolates in the Netherlands, 2016-23.

ABSTRACT:

Objectives

Recently, several MRSA community outbreaks occurred in the Netherlands, including one caused by an impetigo-causing MRSA strain resistant to fusidic acid. Since fusidic acid and flucloxacillin are the main treatment options for impetigo, increasing resistance limits treatment possibilities. We examined trends in fusidic acid resistance percentages among MRSA isolates in the Netherlands.

Materials and methods

Data on routine bacteriological cultures between 2016 and 2023 from 30 laboratories were extracted from the national surveillance system on antimicrobial resistance (ISIS-AR). Fusidic acid resistance percentages per year were calculated both overall and per age group for all MRSA isolates, and more specific, for the subset of MRSA isolates from wound/pus/skin

SUBMITTER: Velthuis F 

PROVIDER: S-EPMC12678940 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature