Pre-pregnancy and gestational cardiometabolic disorders and risk of preterm birth and infant mortality.

ABSTRACT:

Background

Cardiometabolic disorders (CMDs) are common in pregnancy and can harm the offspring's health. While prior studies have explored clustered cardiometabolic risks in pregnancy, most have focused on a limited number of conditions or a single period. We aimed to examine the associations of individual, multiple, and separate and combined patterns of six pre-pregnancy and gestational CMDs with preterm birth and infant mortality.

Methods

Using data from US National Vital Statistics System (2014-2020), we analysed pre-pregnancy CMDs (body mass index, diabetes, hypertension) and gestational CMDs (gestational weight gain, gestational diabetes, hypertensive disorders). We estimated the prevalence and time trends in CMDs using Joinpoint regression models and examined associati

SUBMITTER: Cheng Y 

PROVIDER: S-EPMC12679054 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature