Red blood cell distribution width is associated with renal tubular injury in individuals with type 2 diabetes.

ABSTRACT:

Aims/introduction

Red blood cell distribution width (RDW) is a parameter of erythrocyte volume heterogeneity that has been traditionally used as an indicator of anemia and other hematopoietic abnormalities. Although the RDW-coefficient of variation (RDW-CV) increases in individuals with diabetes, its clinical significance in diabetic kidney disease (DKD), including glomerular and tubular injury, is unclear. Therefore, we aimed to clarify the relationship between RDW-CV and DKD indices in individuals with type 2 diabetes.

Materials and methods

This was a multicenter, retrospective, cross-sectional study. In 490 Japanese individuals with type 2 diabetes (309 men and 181 women), multiple regression analysis was performed to examine the degree of association between DKD indices

SUBMITTER: Miyataka K 

PROVIDER: S-EPMC12679175 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature