A synergistic herbal formulation targeting <i>Malassezia furfur</i> and <i>Staphylococcus epidermidis</i> for effective dandruff management.

ABSTRACT: Dandruff is a chronic scalp condition and the mildest form of seborrheic dermatitis, associated with microbial dysbiosis primarily involving Malassezia furfur and Staphylococcus epidermidis. Conventional anti-dandruff treatments are often limited by recurrence and reliance on synthetic antifungal agents. This study aimed to develop and evaluate a synergistic, oil-based herbal formulation with antimicrobial activity against dandruff-causing microorganisms. The herbal constituent, Eucalyptus citriodora (EC) oil, individually signifies its efficacy against key dandruff-causing microbes, while Centella asiatica and Wedelia trilobata were included for their complementary bioactive and skin-healing properties. A total of three formulations (F1, F2, and F3), con

SUBMITTER: Singh SP 

PROVIDER: S-EPMC12679390 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature