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Clinical Outcomes Post-Transcatheter Aortic Valve Replacement in Patients With Hypertrophic Obstructive Cardiomyopathy.


ABSTRACT:

Background

Patients with hypertrophic obstructive cardiomyopathy (HOCM) were excluded from all major trials for transcatheter aortic valve replacement (TAVR). "Suicide left ventricle" occurring after TAVR is postulated to occur as a result of chronic pressure overload from fixed obstruction that is acutely relieved after the valve deployment resulting in worsening left ventricular outflow tract obstruction.

Aims

The aim of this study was to determine the clinical and readmission outcomes in HOCM patients undergoing TAVR.

Methods

Data was extracted from the National Inpatient and National Readmission 2016-2020 Databases. We performed multivariable Logistic regression analysis to determine the odds of in-hospital mortality and other relevant clinical outcomes in patient

SUBMITTER: Almani MU 

PROVIDER: S-EPMC12679522 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature