No impact of intravenous thrombolysis on post thrombectomy transcranial Doppler pulsatility index.

ABSTRACT:

Background

While transcranial Doppler (TCD) studies are beneficial in evaluating macrovascular recanalization post mechanical thrombectomy (MT), they may have a role in estimating microvascular reperfusion. We aim to (1) evaluate if TCD-derived pulsatility index (PI) ratio is different in large vessel occlusion stroke (LVOS) patients that received intravenous thrombolysis (IVT), indicating potential beneficial impact on microvascular reperfusion, and (2) assess whether TCD metrics correlate with clinical and safety outcomes.

Methods

This is a retrospective analysis of consecutive patients treated with MT for middle cerebral artery (MCA) M1 or intracranial internal carotid artery terminus (ICA) LVOS from January 2018 to June 2024. Patients with Expanded Thrombolysis in Cerebr

SUBMITTER: Jumah A 

PROVIDER: S-EPMC12679829 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature