Triglyceride-glucose index as a key predictor of ARDS in acute pancreatitis: SHAP analysis reveals its critical role in risk stratification.

ABSTRACT:

Background

The relationship between triglyceride-glucose (TyG) index and acute respiratory distress syndrome (ARDS) in acute pancreatitis (AP) patients is still lacking. This study aimed to explore the association between the TyG index and ARDS in AP patients using an 8-year retrospective dataset.

Methods

This study was performed in Changsha Central Hospital from January 2015 to December 2022. Univariate analysis was done to discuss the relationship between different characteristics and ARDS in AP. Multivariate regression analysis was employed to investigate the relationship between the TyG index and ARDS in AP. Eight machine learning models were employed to assess the in-hospital ARDS risk in AP patients. The SHapley Additive exPlanations (SHAP) method was utilized to verif

SUBMITTER: Luo J 

PROVIDER: S-EPMC12679890 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature