Navigator motion-resolved MR fingerprinting using implicit neural representation: Feasibility for free-breathing three-dimensional whole-liver multiparametric mapping.

ABSTRACT:

Purpose

To develop a multiparametric free-breathing three-dimensional, whole-liver quantitative maps of water T₁, water T₂, fat fraction (FF) and R₂*.

Methods

A multi-echo 3D stack-of-spiral gradient-echo sequence with inversion recovery and T₂-prep magnetization preparations was implemented for multiparametric MRI. Fingerprinting and a neural network based on implicit neural representation (FINR) were developed to simultaneously reconstruct the motion deformation fields, the static images, perform water-fat separation, and generate T₁, T₂, R₂*, and FF maps. FINR performance was evaluated in 10 healthy subjects by comparison with quantitative maps generated using conventional breath-holding imaging.

SUBMITTER: Li C 

PROVIDER: S-EPMC12680022 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature